The Nitric Organisms

Nitric Oxide Synthases of Bacteria – and Other Unicellular Organisms

The defining feature of a nitric oxide synthase (NOS) is a heme and pterin-binding oxygenase domain, and enzymes that possess this domain are found in animals and bacteria. While the roles of animal NOS in such processes as vasodilation, neurotransmission, and host defence are understandably important for multicellular life, they are meaningless in bacteria, which makes bacterial NOSs all the m...

Structure diversity of nitric oxide synthases (NOS): the emergence of new forms in photosynthetic organisms

NO SYNTHESIS FROM MAMMALIAN AND PHOTOSYNTHETIC ORGANISMS Humans have enormously increased the level of nitrogen (N) circulating in the troposphere and the earth surface during the last century, correlating with the population increase. As an undesirable consequence, high levels of reactive N are polluting the environment where humans inhabit. Nitric oxide (NO) is one of the reactive N species w...

Nitric oxide and the bioactivities

Nitric oxide (NO), previously known as Endothelium-Derived Relaxing Factor (EDRF) is involved in a wide range of physiological and pathophysiological mechanisms. It is synthesized endogenously by the enzymes Nitric Oxide Synthase (NOS) in specialized tissues from its precursor L-arginine, yielding L-citrulline as a byproduct. It is released by a family of isoenzymes, viz., the endothelial (eNOS...

lsolation of Brucella Organisms from the Milk of Seronegative Cows

Nitric oxide and the bioactivities

Nitric oxide (NO), previously known as Endothelium-Derived Relaxing Factor (EDRF) is involved in a wide range of physiological and pathophysiological mechanisms. It is synthesized endogenously by the enzymes Nitric Oxide Synthase (NOS) in specialized tissues from its precursor L-arginine, yielding L-citrulline as a byproduct. It is released by a family of isoenzymes, viz., the endothelial (eNOS...